Craft your first
pY science pack 1 in a
Research center MK 01: 18 Basic substrate + 3 Glassware → 3 packs. Unlock it with Automation science first, then build the substrate and glassware chains.
1. Research the pack using Automation science
The pY science pack 1 technology requires 90 Automation science packs in the research snapshot, at 30 seconds per unit. Its immediate prerequisite is Latex. You do not need pY science pack 1 to unlock its own first production recipe.
Follow the science progression and the technology page for preceding research. Alternate recipes shown elsewhere may unlock later; use the recipe’s research tier when choosing a first-production route.
2. Build the Basic substrate chain
Basic substrate is the item named fawogae-substrate in the game data. This recipe makes 10 at once from moss, Incubated petri dishes and cellulose. The dish sequence is:
- Make
Empty petri dish from Molten glass at a Glassworks. The early recipe is available with Automation science. - Combine an empty dish with agar to make a loaded Petri dish.
- Incubate the loaded dish at an Microorganism mine.
- Combine the incubated dishes with moss and cellulose in an assembler for Basic substrate.
Empty Petri dishes also have a later Hot air alternative. That later unlock does not replace the earlier Molten glass route. If the production tree suggests an unavailable alternative, change the recipe to the early version.
3. Make Glassware at a Glassworks
Glassware is named flask internally. It needs Molten glass and Rubber stoppers; the recipe produces two Glassware per batch. Stoppers come from:
Keep the substrate and glassware outputs in separate buffers. They are consumed at a 6:1 item ratio for science packs, so balancing them only by matching the number of machines will not necessarily work.
4. Assemble the Research center and start production
Research center MK 01
1 base seconds ·
Burner assembling machine MK 01
The Research center construction recipe consumes an Microorganism mine and a Destructive distillation column. Prepare replacements if those are working machines you still need upstream.
For 30 packs, supply 180 Basic substrate and 30 Glassware. For each individual pack, the direct inputs average 6 substrate and 1 Glassware. The listed 15 seconds is base recipe time; actual output rate depends on the building’s crafting speed and effects.
Move completed packs to labs together with the other science packs required by the technology you select. Making the item and researching with it are separate operations.
Common first-pack bottlenecks
- An assembler cannot select the science recipe: use a Research center, not an ordinary assembler.
- You appear to need the pack before you can make it: check that you chose the early recipe rather than a later alternative.
- Substrate has stopped: follow the incubated-dish chain and check agar, moss and cellulose.
- Glassware has stopped: check both Molten glass and Rubber stoppers.
- A building vanished from the ingredients: construction consumes its listed machine ingredients. Plan separate upstream machines.
Sources, versions and checking
Written from the guide’s recipe export and installed Factorio prototype data, checked 11 November 2026. Recipe quantities use the FactorioLab full-suite snapshot retrieved 3 November 2026 (Factorio 2.1.21, pY Alien Life 3.1.8). Fuel behavior and breeding probabilities were checked against installed Factorio 2.1.24 prototypes with pY Alien Life 3.1.8. Research costs use the guide’s separate resolved technology snapshot.
This is a data-checked walkthrough, not a recorded playthrough. Startup settings, other mod versions and different mod combinations can change recipes. Quantities shown with fractions are expected yields. Base recipe seconds do not include machine speed, fuel or electricity. Follow the linked item pages to compare alternatives.
